Please refer to the solubility information to select the appropriate solvent.
Biological activity
Description
CAS NO.：796073-69-3 Product Name：DM4 Synonyms：N2'-deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine;L-DM4;N2'-DEACETYL-N2'-(4-MERCAPTO-4-METHYL-1-OXOPENTYL)-MAYTANSINE;;DM4 EINEC: Molecular Formula：C38H54N3O10SCL Molecular Weight：780.367
Target:
In Vivo
In Vitro
DM4, a structural analogue of maytansine, is a new thiol-containing and potent maytansinoid. DM4 is a cytotoxic maytansinoid drug. It is synthesized in order to link maytansinoids to antibodies via disulfide bonds. Maytansinoids inhibit tubulin polymerization and microtubule assembly and enhance microtubule destabilization, so there is potent suppression of microtubule dynamics resulting in a mitotic block and subsequent apoptotic cell death[1].
Kinase Assay
Cell Assay
Animal Administration
References
Return Policy
If you are in any way unsatisfied with your purchase, you may return any item(s) within 365 days of its original purchase date.
Please provide your Order Number in the email. We strive to reply to all email inquiries within one business day.
