Mitoguazone Datasheet DC Chemicals
Description Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment.
Cat.No DC40068
Name Mitoguazone

Chemical Properties

CAS 459-86-9
Formula C5H12N8
MW 184.20
Storage Powder-20°C3 years4°C2 yearsIn solvent-80°C6 months-20°C1 month

References

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