Mutant IDH1-IN-1 Datasheet DC Chemicals

Description	Mutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 uM(A level in Patent).
Cat.No	DC7982
Name	Mutant IDH1-IN-1

Chemical Properties

CAS	1355326-21-4
Formula	C30H31FN4O2
MW	498.59
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Deng G, et al. Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. J Biol Chem. 2015 Jan 9;290(2):762-74.

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