NSC59984 Datasheet DC Chemicals
Description NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway.The EC50 of NSC59984 in most cancer cells is significantly lower than those of normal cells, with EC50 of 8.38 μM for p53-null HCT116 cells.
Cat.No DC9257
Name NSC59984

Chemical Properties

CAS 803647-40-7
Formula C12H15N3O4
MW 265.27
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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