NVP-LCQ195 Datasheet DC Chemicals

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Cat.No	DC9392
Name	NVP-LCQ195

Chemical Properties

CAS	902156-99-4
Formula	C17H19CL2N5O4S
MW	460.3349
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target:	Cdk5/p25:1 nM (IC50) CDK5/p35:1 nM (IC50) Cdk1/cyclin B:2 nM (IC50) cdk2/cyclin A:2 nM (IC50) CDK2/cyclinE:5 nM (IC50) CDK9/cyclinT1:15 nM (IC50) CDK3/Cyclin E:42 nM (IC50) cdk6/cyclin D3:187 nM (IC50) CDK7/Cyclin H/MAT1:3564 nM (IC50)
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. McMillin DW, Delmore J, Negri J et al. Molecular and cellular effects of multi-targeted cyclin-dependent kinase inhibition in myeloma: biological and clinical implications. Br J Haematol. 2011 Feb;152(4):420-32.

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