Nattokinase Datasheet DC Chemicals
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Cat.No DCAPI1056
Name Nattokinase

Chemical Properties

CAS 133876-92-3
Formula C20H23BCL2N2O9
MW 517.1216
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：133876-92-3
Product Name：Nattokinase
Synonyms：NattoLife;Nattokinase;Nattoesse Haruno-Ogawa;MLN9708;4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid;Ixazomib Citrate (MLN9708);ixazomib citrate 1,3,2-dioxaborinane;4-(carboxymethyl)-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid;4-(carboxymethyl)-2-[(1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid;1,3,2-Dio
EINEC:
Molecular Formula：C20H23BCL2N2O9
Molecular Weight：517.1216
Target:
In Vivo Nattokinase (150-250 mg/kg; oral gavage twice daily for 2 days) exhibits fibrinolytic activity and dissolves blood clots in vivo[3]. Animal Model: Sprague-Dawley (SD) rats (180-220 g) are injected κ-Carrageenan[3] Dosage: 150, 250 mg/kg Administration: Oral gavage twice daily for 2 days Result: Increased the plasma concentration of fibrin/fibrinogen degradation products (FDPs) and D-Dimer in a dose-dependent manner. Decreased the fraction of the vessel cross section occupied by thrombosis.
In Vitro Nattokinase dissolves 94% blood clot at ten minutes and degrades the fibrin clot after two hours of incubation[2].
Kinase Assay
Cell Assay
Animal Administration

References

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