Necrostatin 2 racemate Datasheet DC Chemicals

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Cat.No	DC10551
Name	Necrostatin 2 racemate

Chemical Properties

CAS	852391-15-2
Formula	C13H12CLN3O2
MW	277.708
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target:	IC50 Value: 50 nM (EC50) [1] Target: TNF-alpha
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Teng X, Keys H, Jeevanandam A, Structure-activity relationship study of [1,2,3]thiadiazole necroptosis inhibitors. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6836-40. [2]. Jagtap PG, Degterev A, Choi S, Structure-activity relationship study of tricyclic necroptosis inhibitors. J Med Chem. 2007 Apr 19;50(8):1886-95. [3]. Teng X, Degterev A, Jagtap P, Structure-activity relationship study of novel necroptosis inhibitors. Bioorg Med Chem Lett. 2005 Nov 15;15(22):5039-44.

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