O-Desmethyl gefitinib Datasheet DC Chemicals

Description	O-Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O-desmethyl gefitinib is dependent on CYP2D6 activity. O-desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays.
Cat.No	DC28069
Name	O-Desmethyl gefitinib

Chemical Properties

CAS	847949-49-9
Formula	C21H22CLFN4O3
MW	432.88
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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