OPC 21268 Datasheet DC Chemicals

Description	OPC-21268 is a vasopressin 1 receptor antagonist potentially for the treatment of heart failure and hypertension.
Cat.No	DC10726
Name	OPC 21268

Chemical Properties

CAS	131631-89-5
Formula	C26H31N3O4
MW	449.54
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Yamamura Y, et al. OPC-21268, an orally effective, nonpeptide vasopressin V1 receptor antagonist. Science. 1991 Apr 26;252(5005):572-4. [2]. Bemana I, et al. Treatment of brain edema with a nonpeptide arginine vasopressin V1 receptor antagonist OPC-21268 in rats. Neurosurgery. 1999 Jan;44(1):148-54.

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