Description |
Omalizumab is a monoclonal antibody targeting the high-affinity receptor binding site on human immunoglobulin (Ig)E to treat an asthma attack. |
Cat.No |
A015 |
Name |
Omalizumab |
Chemical Properties
CAS |
242138-07-4 |
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Synonyms |
Immunoglobulin G1,anti-(human immunoglobulin E Fc region) (human-mouse monoclonal E25 clonepSVIE25 g-chain), disulfide withhuman-mouse monoclonal E25 clone pSVIE25 k-chain, dimer (9CI);Immunoglobulin G1,anti-(human immunoglobulin E Fc region) (human-mouse monoclonal E25 clonepSVIE25 g-chain), disulfide withhu;Olizumab;rhuMab-E 25;Xolair;Omalizumab;12239-06-4;Tryptophanase;242138-07-4;UMDARFJWVLMIOM-UHFFFAOYSA-N;UMDARFJWVLMIOM-UHFFFAOYSA-N;(1R,3E)-3-(2,2-dimethylpropylidene)-2-methylidenecyclohexan-1-ol;(1R,3Z)-3-(2,2-dimethylpropylidene)-2-methylidenecyclohexan-1-ol;(1S,3Z)-3-(2,2-dimethylpropylidene)-4-methylidenecyclohexan-1-ol;(1R,3Z)-3-(2,2-dimethylpropylidene)-4-methylidenecyclohexan-1-ol;(1R,3E)-3-(2,2-dimethylpropylidene)-2-methylidenecyclohexan-1-ol;(1R,3Z)-3-(2,2-dimethylpropylidene)-2-methylidenecyclohexan-1-ol;(1S,3Z)-3-(2,2-dimethylpropylidene)-4-methylidenecyclohexan-1-ol;(1R,3Z)-3-(2,2-dimethylpropylidene)-4-methylidenecyclohexan-1-ol;33748-00-4;DA-66462;33748-00-4;DA-58782;DA-66462;9012-00-4;DA-58782;9012-00-4;69227-09-4;69227-09-4;9024-00-4;9024-00-4 |
pH value |
Corresponds to reference standard: PASS |
Non-reduced CE-SDS |
98.6% |
SEC-HPLC |
99.3% |
Isoelectric Point |
Corresponds to reference standard:PASS |
Bacterial Endotoxins Test |
<1 EU/ml |
Residual Proteins of Host Cell |
|
Exogenous Residual DNA |
1 pg/mg |
Residual protein A |
<1 ng/mg |
Biological Activity |
Compared with standard, the range of biological activity is 103% |
Osmolality |
Corresponds to reference standard: PASS |
Peptide mapping |
Corresponds to reference standard: PASS |
N-terminal sequence |
Corresponds to reference standard:PASS |
References
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