P2X3 antagonist 34 Datasheet DC Chemicals

Description	P2X3 antagonist 34 is a potent, selective and orally active P2X3 homotrimeric receptor antagonist with IC50s of 25?nM, 92?nM and 126?nM for human P2X3, rat P2X3 and guinea pig P2X3 receptors, respectively. P2X3 antagonist 34 is less active against human, rat and guinea pig P2X2/3 heterotrimeric receptors. P2X3 antagonist 34 has strong anti-tussive effect.
Cat.No	DC40785
Name	P2X3 antagonist 34

Chemical Properties

CAS	2417288-67-4
Formula	C24H26F2N4O3
MW	456.49
Storage	-20°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References

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