PCI-34051 Datasheet DC Chemicals

Description	PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM.
Cat.No	DC1109
Name	PCI-34051

Chemical Properties

CAS	950762-95-5
Formula	C17H16N2O3
MW	296.32
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Balasubramanian S, et al. A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas. Leukemia. 2008 May;22(5):1026-34. [2]. Ren Y, et al. Therapeutic effects of histone deacetylase inhibitors in a murine asthma model. Inflamm Res. 2016 Dec;65(12):995-1008.

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