LIPID PL1 Datasheet DC Chemicals

Description	PL1 is a novel biomimetic phospholipid. PL1 nanoparticle delivery of costimulatory receptor CD137 mRNA improved the immunotherapy with an anti-CD137 Ab to some extent in both tumor models with better results obtained in the B16F10 melanoma model as compared to the A20 lymphoma model.
Cat.No	DC80068
Name	LIPID PL1

Chemical Properties

CAS	2274812-94-9
Formula	C61H121N2O10P
MW	1073.6
Storage	-20

References

Biomimetic nanoparticles deliver mRNAs encoding costimulatory receptors and enhance T cell mediated cancer immunotherapy-By: Li, Wenqing; Zhang, Xinfu ; Zhang, Chengxiang; Yan, Jingyue; Hou, Xucheng ; Du, Shi; Zeng, Chunxi; Zhao, Weiyu; Deng, Binbin; McComb, David W. ; et al Nature Communications (2021), 12(1), 7264 | Language: English, Database: CAplus and MEDLINE

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