PLB-1001 Datasheet DC Chemicals

Description	Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) is a ATP-competitive small-molecule inhibitor, binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily[1].
Cat.No	DC12462
Name	PLB-1001

Chemical Properties

CAS	1440964-89-5
Formula	C20H15F3N8
MW	424.391
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1]. Hu H, et al. Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor. Cell. 2018 Nov 29;175(6):1665-1678.e18.

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