Vonafexor(PLX007,EYP-001) Datasheet DC Chemicals

Description	Vonafexor (EYP001) is a selective FXR agonist with anti-HBV effects.
Cat.No	DC31030
Name	Vonafexor(PLX007,EYP-001)

Chemical Properties

CAS	1192171-69-9
Formula	C19H15CL3N2O5S
MW	489.76
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Joly S, et al. The selective FXR agonist EYP001 is well tolerated in healthy subjects and has additive anti-HBV effect with nucleoside analogues in HepaRG cells. J Hepatol 66(1):S690. [2]. Fiorucci S,et al. Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH) [published online ahead of print, 2020 Jun 19]. Expert Opin Investig Drugs. 2020;1-10.

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