PPZ-A10 Datasheet DC Chemicals

Description	PPZ-A10 is an ionizable cationic lipid.It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo. Intraperitoneal administration of LNPs containing PPZ-A10 and encapsulating an mRNA reporter preferentially accumulates in hepatic Kupffer cells and splenic macrophages in mice.
Cat.No	DC82102
Name	PPZ-A10

Chemical Properties

CAS	2941268-67-1
Formula	C56H114N6O2
MW	903.6
Storage

References

1. Subhan, M.A., and Torchilin, V.P. Biopolymer-based nanosystems for siRNA drug delivery to solid tumors including breast cancer. Pharmaceutics 15(1), 153 (2023). 2. Ni, H., Hatit, M.Z.C., Zhao, K., et al. Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo. Nat. Commun. 13(1), 4766 (2022).

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