Phenamil methanesulfonate Datasheet DC Chemicals

Description	Phenamil methanesulfonate, an analog of Amiloride, is a more potent and less reversible epithelial sodium channel (ENaC) blocker with an IC50 of 400 nM. Phenamil methanesulfonate is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca2+ transport with an IC50 of 140 nM in a Ca2+ uptake assay. Phenamil methanesulfonate is an intriguing small molecule to promote bone repair by strongly activating BMP signaling pathway. Phenamil methanesulfonate is used for the research of cystic fibrosis lung disease.
Cat.No	DC40101
Name	Phenamil methanesulfonate

Chemical Properties

CAS	1161-94-0
Formula	C12H12N7OCL.CH4O3S
MW	401.82864
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

References

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