Pifithrin-α, p-Nitro, Cyclic Datasheet DC Chemicals
Description Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-α in protecting cortical neurons exposed to Etoposide (ED50=30 nM). Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue.
Cat.No DC28442
Name Pifithrin-α, p-Nitro, Cyclic

Chemical Properties

CAS 60477-38-5
Formula C15H13N3O2S
MW 299.35
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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