Pradefovir mesylate (Remofovir mesylate) Datasheet DC Chemicals

Description	Pradefovir mesylate is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a Km of 60 μM.
Cat.No	DC12202
Name	Pradefovir mesylate (Remofovir mesylate)

Chemical Properties

CAS	625095-61-6
Formula	C18H23CLN5O7PS
MW	519.9
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Lin CC, et al. Metabolic activation of Pradefovir by CYP3A4 and its potential as an inhibitor or inducer. Antimicrob Agents Chemother. 2006 Sep;50(9):2926-31.

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