Prucalopride Datasheet DC Chemicals
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Cat.No DC4147
Name Prucalopride

Chemical Properties

CAS 179474-81-8
Formula C18H26CLN3O3
MW 367.87
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target: IC50 value: 8.6/8.1 for 5-HT4a/4b(pKi) Target: 5-HT4 receptor
In Vivo
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Briejer MR, et al. The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. Eur J Pharmacol. 2001 Jun 29;423(1):71-83. [2]. Emmanuel AV, et al. Randomised clinical trial: the efficacy of prucalopride in patients with chronic intestinal pseudo-obstruction--a double-blind, placebo-controlled, cross-over, multiple n = 1 study. Aliment Pharmacol Ther. 2012 Jan;35(1):48-55. [3]. Bouras EP, et al. Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. Gut. 1999 May;44(5):682-6.
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