Purvalanol A(NG 60) Datasheet DC Chemicals

Description	Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor.
Cat.No	DC8075
Name	Purvalanol A(NG 60)

Chemical Properties

CAS	212844-53-6
Formula	C19H25CLN6O
MW	388.89
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Gray NS, et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science. 1998 Jul 24;281(5376):533-8. [2]. Bain J, et al. The specificities of protein kinase inhibitors: an update. Biochem J. 2003 Apr 1;371(Pt 1):199-204. [3]. Villerbu N, et al. Cellular effects of purvalanol A: a specific inhibitor of cyclin-dependent kinase activities. Int J Cancer. 2002 Feb 20;97(6):761-9.

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