Pyridostatin Datasheet DC Chemicals
Description Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB). Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets gene bodies containing clusters of sequences with a propensity for G-quadruplex formation. As a result, pyridostatin modulated the expression of these genes, including the proto-oncogene SRC.
Cat.No DC32501
Name Pyridostatin

Chemical Properties

CAS 1472611-44-1
Formula C33H33F3N8O7
MW 710.66
Storage

References

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