R-7050 Datasheet DC Chemicals

Description	R-7050 is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.
Cat.No	DC10897
Name	R-7050

Chemical Properties

CAS	303997-35-5
Formula	C16H8CLF3N4S
MW	380.77
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Gururaja TL, et al. A class of small molecules that inhibit TNFalpha-induced survival and death pathways viaprevention of interactions between TNFalphaRI, TRADD, and RIP1. Chem Biol. 2007 Oct;14(10):1105-18. [2]. King MD, et al. TNF-alpha receptor antagonist, R-7050, improves neurological outcomes following intracerebralhemorrhage in mice. Neurosci Lett. 2013 May 10;542:92-6.

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