RU-SKI43 HCl Datasheet DC Chemicals
Description RU-SKI 43 is an inhibitor of Hat. It blocks palmitoylation of Shh without affecting palmitoylation of H-Ras or Fyn, myristoylation of c-Src, or acylation of Wnt3a. RU-SKI-43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR.
Cat.No DC33637
Name RU-SKI43 HCl

Chemical Properties

CAS 1782573-67-4
Formula C22H31CLN2O2S
MW 423.012
Storage

References

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