RWJ-56110 dihydrochloride Datasheet DC Chemicals

Description	RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), quite selective relative to U46619. RWJ-56110 dihydrochloride blocks angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 dihydrochloride induces cell apoptosis.
Cat.No	DC40104
Name	RWJ-56110 dihydrochloride

Chemical Properties

CAS	2387505-58-8
Formula
MW
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

References

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