RX-3117 Datasheet DC Chemicals

Description	RX-3117 is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity.
Cat.No	DC7762
Name	RX-3117

Chemical Properties

CAS	865838-26-2
Formula	C10H12FN3O4
MW	257.22
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Peters GJ, et al. Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360). Invest New Drugs. 2013 Dec;31(6):1444-57. [2]. Yang MY, et al. A novel cytidine analog, RX-3117, shows potent efficacy in xenograft models, even in tumors that are resistant to gemcitabine. Anticancer Res. 2014 Dec;34(12):6951-9.

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