R-268712 Datasheet DC Chemicals

Description	Potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC50 = 2.5 nM). Exhibits ~ 5000-fold selectivity over p38 MAPK. Suppresses development of renal fibrosis in a unilateral ureteral obstruction model. Also reduces proteinuria, glomeruloscler
Cat.No	DC8022
Name	R-268712

Chemical Properties

CAS	879487-87-3
Formula	C20H18FN5O
MW	363.39
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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