(Rac)-BRD0705 Datasheet DC Chemicals

Description	(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC50 of 66 nM and a Kd of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML).
Cat.No	DC28365
Name	(Rac)-BRD0705

Chemical Properties

CAS	1597440-03-3
Formula	C20H23N3O
MW	321.42
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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