Rolapitant free base Datasheet DC Chemicals
Description Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). This may prevent both SP-induced emesis and chemotherapy-induced nausea and vomiting (CINV).
Cat.No DC31413
Name Rolapitant free base

Chemical Properties

CAS 5552292-08-7
Formula C25H26F6N2O2
MW 500.4854
Storage

References

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