(S)-Crizotinib Datasheet DC Chemicals
Description (S)-Crizotinib is an MTH1 inhibitor. By inhibiting MTH1, (S)-Crizotinib disrupts nucleotide pool homeostasis, induces an increase in DNA single-strand breaks, activates DNA repair in human colon carcinoma cells, and effectively suppresses tumor growth in animal models.
Cat.No DC34018
Name (S)-Crizotinib

Chemical Properties

CAS
Formula C21H22CL2FN5O
MW 450.3394
Storage

References

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