SB-277011 hydrochloride Datasheet DC Chemicals

Description	SB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, orally bioavailable and brain penetrate?dopamine D3?receptor (D3R)?antagonist with Ki values of 10.7?nM and?11.2 nM?at?rodent and human?D3R, respectively. SB-277011 hydrochloride displays 80- to 100-fold selectivity over other dopamine receptors with?pKis of 8.0, 6.0, <5.2, and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively.
Cat.No	DC40102
Name	SB-277011 hydrochloride

Chemical Properties

CAS	215804-67-4
Formula	C28H31CLN4O
MW	475.02
Storage	Powder-20°C3 years4°C2 yearsIn solvent-80°C6 months-20°C1 month

References

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