SHR0302 Datasheet DC Chemicals

Description	SHR0302 is a potent and orally active all members of the JAK family inhibitor, particularly JAK1. The selectivity of SHR0302 for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. SHR0302 inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. SHR0302 has anti-proliferative and anti-inflammatory effects.
Cat.No	DC40168
Name	SHR0302

Chemical Properties

CAS	1445987-21-2
Formula	C18H22N8O2S
MW	414.48
Storage	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

References

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