SIAIS178 Datasheet DC Chemicals
Description SIAIS178 is a potent and selective BCR-ABL degrader based on PROTAC technology with an IC50 of 24 nM. SIAIS178 causes effective degradation of BCR-ABL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. SIAIS178 has anticancer activity.
Cat.No DC28539
Name SIAIS178

Chemical Properties

CAS 2376047-73-1
Formula C50H62CLN11O6S2
MW 1012.68
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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