SMS1-IN-1 Datasheet DC Chemicals

Description	SMS1-IN-1, compound SAPA 1j, is a novel and the most potent sphingomyelin synthase 1 (SMS1) inhibitor with an IC50 value of 2.1 μM. SMS1-IN-1 has the potential for the treatment of atherosclerosis.
Cat.No	DC28899
Name	SMS1-IN-1

Chemical Properties

CAS	1807943-38-9
Formula	C23H23BRN2O4S
MW	503.41
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Li YL, et al. Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors.Bioorg Med Chem. 2015 Sep 15;23(18):6173-84.

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