SU4312(NSC86429) Datasheet DC Chemicals

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Cat.No	DC9781
Name	SU4312(NSC86429)

Chemical Properties

CAS	5812-07-7
Formula	C17H16N2O
MW	264.32
Storage

Biological activity

Description
Target:	PDGFR Flk-1
In Vivo
In Vitro	Receptor tyrosine kinases (RTKs) have been shown to be important mediators of cellular signal transduction in cells. Many RTKs have been shown to be oncogene products implicating their role in the transformation process associated with human cancers[1].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. L Sun, et al. Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases. J Med Chem. 1998 Jul 2;41(14):2588-603.

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