Salermide Datasheet DC Chemicals

Description	Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells, salermide causes 90% apoptosis within 72 hours (IC50 ~ 20 μM) by reactivating proapototic genes that are repressed by SIRT1.
Cat.No	DC10002
Name	Salermide

Chemical Properties

CAS	1105698-15-4
Formula	C26H22N2O2
MW	394.47
Storage	4°C for 1 year, -20°C for more than 2 years

References

[1]. Lara E, et al. Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. Oncogene. 2009 Feb 12;28(6):781-91.

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