Description
Secukinumab is a fully human immunoglobulin G1-kappa monoclonal antibody that directly inhibits interleukin (IL)-17A, has been shown to have robust efficacy in the treatment of moderate-to-severe psoriasis (PsO), psoriatic arthritis (PsA), and ankylosing
Cat.No
A019
Name
Secukinumab
Chemical Properties
CAS
875356-43-7
Synonyms
Secukinumab;Secukinumab/Secukinumab(Hchain);Secukinuma;875356-43-7
pH value
Corresponds to reference standard: PASS
Non-reduced CE-SDS
98.8%
SEC-HPLC
99.1%
Isoelectric Point
Corresponds to reference standard:PASS
Bacterial Endotoxins Test
<1 EU/ml
Residual Proteins of Host Cell
Exogenous Residual DNA
<1 pg/mg
Residual protein A
<1 ng/mg
Biological Activity
Compared with standard, the range of biological activity is 112%
Osmolality
Corresponds to reference standard: PASS
Peptide mapping
Corresponds to reference standard: PASS
N-terminal sequence
Corresponds to reference standard:PASS
References
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