Simvastatin acid ammonium Datasheet DC Chemicals

Description	Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.
Cat.No	DC28401
Name	Simvastatin acid ammonium

Chemical Properties

CAS	139893-43-9
Formula	C25H43NO6
MW	453.61
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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