TG6-129 Datasheet DC Chemicals
Description TG6-129 is an antagonist of the EP2 receptor, suppressing PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 μM. It is without effect on EP4, DP1, IP, and β2-adrenergic receptors. TG6-129 reduces the expression of COX-2, IL-1β, IL-12, IL-23, IL-6, and TNF-α induced by the EP2-selective agonist butaprost in P388D1 macrophages.
Cat.No DC33352
Name TG6-129

Chemical Properties

CAS 1164464-14-5
Formula C20H18FN5O3S3
MW 491.57
Storage

References

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