TH-34 Datasheet DC Chemicals
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Cat.No DC12487
Name TH-34

Chemical Properties

CAS 2196203-96-8
Formula C15H16N2O2
MW 256.12
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target: HDAC6:4.6 μM (IC50) HDAC8:1.9 μM (IC50) HDAC10:7.7 μM (IC50)
In Vivo
In Vitro TH34 induces caspase-dependent programmed cell death and cell cycle arrest in neuroblastoma cells[1].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Kolbinger FR, et al. The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines. Arch Toxicol. 2018 Aug;92(8):2649-2664.
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