THZ-P1-2 Datasheet DC Chemicals

Description	THZ-P1-2 is a first-in-class and selective PI5P4K inhibitor, with an IC50 of 190 nM for PI5P4Kα. THZ-P1-2 covalently targets cysteines on a disordered loop in PI5P4Kα/β/γ. THZ-P1-2 causes autophagy disruption and upregulates TFEB signaling. THZ-P1-2 displays anticancer activity in leukemia cell lines.
Cat.No	DC40896
Name	THZ-P1-2

Chemical Properties

CAS	2058075-45-7
Formula	C31H29N7O2
MW	531.61
Storage	4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References

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