TRPM8 antagonist 14 Datasheet DC Chemicals

Description	TRPM8 Antagonist is a potent and selective TRPM8 antagonist, with an IC50 of 0.2 nM, used in the research of neuropathic pain syndromes.
Cat.No	DC11472
Name	TRPM8 antagonist 14

Chemical Properties

CAS	259674-19-6
Formula	C26H26N2O2
MW	398.50
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Bertamino A, et al. Identification of a Potent Tryptophan-Based TRPM8 Antagonist With in Vivo Analgesic Activity. J Med Chem. 2018 Jul 10. doi: 10.1021/acs.jmedchem.8b00545.

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