TX1-85-1 Datasheet DC Chemicals
Description TX1-85-1 is a potent, selective, ATP-competitive Her3 (ErbB3) inhibitor with IC50 of 23 nM, forms a covalent bond with Cys721 located in the ATP-binding site of Her3.
Cat.No DC12480
Name TX1-85-1

Chemical Properties

CAS 1603845-32-4
Formula C32H36N8O3
MW 580.693
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Xie T, et al. Pharmacological targeting of the pseudokinase Her3. Nat Chem Biol. 2014 Dec;10(12):1006-12.
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