UNIL-088 Datasheet DC Chemicals
Description UNIL088 is a water-soluble prodrug of cyclosporine A (CsA) designed for topical ocular delivery. The pro-moiety is grafted via an ester function to CsA and the solubilizing group is a phosphate ion. UNIL-088 can be rapidly hydrolysed under physiological conditions, and can retain a long shelf-life in aqueous media. UNIL-088 is more stable at pH 5 than at pH 7 with conversion rate constant of 3.2 x 10(-3) and 26.0 x 10(-3)days(-1), respectively.
Cat.No DC32803
Name UNIL-088

Chemical Properties

CAS 473545-11-8
Formula C73H128N13O22P
MW 1570.8698
Storage

References

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