VRT043198 Datasheet DC Chemicals
Description VRT-043198, the active metabolite of VX-765 (Belnacasan), is a Caspase inhibitor. VRT-043198 exhibits 100- to 10,000-fold selectivity against other caspase-3 and -6 to -9. VRT-043198 inhibited the release of interleukin (IL)-1beta and IL-18, but it had little effect on the release of several other cytokines, including IL-1alpha, tumor necrosis factor-alpha, IL-6 and IL-8.
Cat.No DC31342
Name VRT043198

Chemical Properties

CAS 244133-31-1
Formula C22H29CLN4O6
MW 480.94
Storage

References

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