| Description |
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease. |
| Cat.No |
A023 |
| Name |
Vedolizumab |
Chemical Properties
| CAS |
943609-66-3 |
|
| Synonyms |
Vedolizumab;943609-66-3;DA-78851;3-Methylidene-7-(2-tritiopyrazolo[1,5-a]pyridine-3-carbonyl)-2,7-diazaspiro[4.4]nonan-1-one;3-methylidene-7-(6-tritiopyrazolo[1,5-a]pyridine-3-carbonyl)-2,7-diazaspiro[4.4]nonan-1-one;3-methylidene-7-(7-tritiopyrazolo[1,5-a]pyridine-3-carbonyl)-2,7-diazaspiro[4.4]nonan-1-one;Anti-Human lymphocyte α4β7 integrin, Humanized Antibody |
| pH value |
Corresponds to reference standard： PASS |
| Non-reduced CE-SDS |
98.5% |
| SEC-HPLC |
99.6% |
| Isoelectric Point |
Corresponds to reference standard:PASS |
| Bacterial Endotoxins Test |
＜1 EU/ml |
| Residual Proteins of Host Cell |
|
| Exogenous Residual DNA |
＜1 pg/mg |
| Residual protein A |
＜1 ng/mg |
| Biological Activity |
Compared with standard, the range of biological activity is 104% |
| Osmolality |
Corresponds to reference standard: PASS |
| Peptide mapping |
Corresponds to reference standard: PASS |
| N-terminal sequence |
Corresponds to reference standard:PASS |
References
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