Vimirogant hydrochloride Datasheet DC Chemicals

Description	Vimirogant (VTP-43742) hydrochloride is a potent, selective, and orally active RORγt inhibitor (Ki=3.5 nM; IC50=17 nM). Vimirogant hydrochloride exhibits >1000-fold selectivity versus the RORα and RORβ isotypes. Vimirogant hydrochloride inhibits Th17 differentiation and IL-17A secretion from mouse splenocytes (IC50=57 nM) without affecting Th1, Th2, or Treg cell differentiation. Vimirogant hydrochloride has the potential for autoimmune disorders research.
Cat.No	DC40046
Name	Vimirogant hydrochloride

Chemical Properties

CAS
Formula	C27H35F3N4O3S.XHCL
MW
Storage	Powder-20°C3 years4°C2 yearsIn solvent-80°C6 months-20°C1 month

References

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