WAY-262611 Datasheet DC Chemicals
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Cat.No DC7744
Name WAY-262611

Chemical Properties

CAS 1123231-07-1
Formula C20H22N4
MW 318.42
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target:
In Vivo WAY-262611 has excellent pharmacokinetic properties and shows a dose dependent increase in the trabecular bone formation rate in ovariectomized rats following oral administration. Calvariae from wt mice treated with WAY-262611 shows statistically increased BFR, while similarly treated KO animals are no different from control. This indicates that WAY-262611 is acting via the Wnt β-catenin pathway and most likely through inhibition of Dkk-1[1].
In Vitro WAY-262611 has the most potent activity in the primary assay, low kinase inhibition potential, and high solubility[1].
Kinase Assay
Cell Assay
Animal Administration

References

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