WF-47-JS03 Datasheet DC Chemicals

Description	WF-47-JS03 is a potent and selective RET kinase inhibitor with IC50s of 1.7 nM and 5.3 nM for KIF5B-RET transfected Ba/F3 cells and CCDC6-RET transfected LC-2/ad lung cancer cells, respectively. WF-47-JS03 demonstrates >500-fold selectivity against kinase insert domain receptor (KDR). Effective brain penetration.
Cat.No	DC40625
Name	WF-47-JS03

Chemical Properties

CAS
Formula	C30H38N6O2
MW	514.66
Storage	Powder-20°C3 years4°C2 yearsIn solvent-80°C6 months-20°C1 month

References

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