WZ4002-hydroxy Datasheet DC Chemicals
Description WZ4002-hydroxy is a WZ4002 (MedKoo Cat#: 203170) derivative or WZ4002 analog. In which the methoxy group is replaced by hydroxy group. WZ4002 is EGFR inhibitor against EGFR T790M (mutation of the gatekeeper T790 residue) which is detected in 50% of clinically resistant patients to gefitinib or erlotinib. WZ4002 has a basic chemical framework (covalent pyrimidine) which is different from that of other EGFR inhibitors.
Cat.No DC38083
Name WZ4002-hydroxy

Chemical Properties

CAS
Formula C24H25CLN6O3
MW 480.953
Storage

References

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